Publications
2024 Zborowsky, S., R. Tahan, D. Lindell. Adaptive loss of tRNA gene expression leads to phage resistance in a marine Synechococcus cyanobacterium. Nature Microbiology. In press.
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2024 Weissenbach, J., S. Goldin, Y. Hulata, D. Lindell. Differences in cyanophage and virioplankton production dynamics in eddies of opposite polarity in the North Pacific Subtropical Gyre. Frontiers in Marine Science 11:1442290. https://doi.org/10.3389/fmars.2024.1442290
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2024 Beckett, S.J., D. Demory, A.R. Coenen, J.R. Casey, M. Dugenne, C.L. Follett, P. Connell, M.C.G. Carlson, S.K. Hu, S.T. Wilson, D. Muratore, R.A. Rodriguez-Gonzalez, S. Peng, K.W. Becker, D.R. Mende, E.V. Armbrust, D.A. Caron, D. Lindell, A.E. White, F. Ribalet, J.S. Weitz. Disentangling top-down drivers of mortality underlying diel population dynamics of Prochlorococcus in the North Pacific Subtropical Gyre. Nature Communications. 15:2105, Link to the paper: https://doi.org/10.1038/s41467-024-46165-3
2023 Park, J., B.P. Durham, R.S. Key, R.D. Groussman, P. Pinedo-Gonzalez, N.J. Hawco, S.G. John, M.C.G. Carlson, D. Lindell, L. Juranek, S. Ferron, F. Ribalet, E.V. Armbrust, A.E. Ingalls, R.M. Bundy. Siderophore production and utilization by marine bacteria in the North Pacific Ocean. Limnology and Oceanography. 68:1636-1653, Link to the paper: http://dx.doi.org/10.1002/lno.12373
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2022 Baran, N., M.C.G. Carlson, G. Sabehi, M. Peleg, K. Kondratyeva, I. Pekarski, D. Lindell. Widespread yet persistent low abundance of TIM5-like cyanophages in the oceans. Environental Microbiology. 24:6476-6492. Link to the paper: https://doi.org/10.1111/1462-2920.16210
2022 Maidanik, I., S. Kirzner, I. Pekarski, L. Arsenieff, R. Tahan, M.C.G. Carlson, D. Shitrit, N. Baran, S. Goldin, J.S. Weitz and D. Lindell. Cyanophages from a less virulent clade dominate over their sister clade in the oceans. ISME J. 6:2169-2180. Link to the paper: https://www.nature.com/articles/s41396-022-01259-y
2022 Carlson, M.C.G., F. Ribalet, I. Maidanik, B.P. Durhman, Y. Hulata, S. Ferron, J. Weissenbach, N. Shamir, S. Goldin, N. Baran, B.B. Cael, D.M. Karl, A. White, E.V. Armbrust and D. Lindell. Viruses affect picocyanobacterial abundance and biogeography in the North Pacific Ocean. Nature Microbiology 7:570-580. Link to the paper: https://www.nature.com/articles/s41564-022-01088-x. See News & Views about this study at Nature Microbiology 7:480-481.
2022 Shitrit, D., T. Hackl, R. Laurenceau, N, Raho, M.C.G. Carlson, G. Sabehi, D.A. Schwartz, S.W. Chisholm and D. Lindell. Genetic engineering of marine cyanophages reveals integration but not lysogeny in T7-like cyanophages. ISME J. 16:488-499. (Early online August 2021.) Link to the paper: https://rdcu.be/cvZcM.
2021 Sawaya*, N.A., N. Baran*, S. Mahank, A. Varsani, D. Lindell^, M. Breitbart^. Adaptation of the polony technique to quantify Gokushovirinae, a diverse group of single-stranded DNA phage. Environ. Microbiol. 23:6622-6636. *equal contribution. ^corresponding authors.
Link to the paper: https://enviromicro-journals.onlinelibrary.wiley.com/doi/10.1111/1462-2920.15805
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2021 Marwat*, N., M.C.G. Carlson*, S. Goldin, F. Ribalet, S. Kirzner, Y. Hulata, S.J. Beckett, D. Shitrit, J.S. Weitz, E.V. Armbrust and D. Lindell. A single-cell polony method reveals low levels of infected Prochlorococcus in oligotrophic waters despite high cyanophage abundances. ISME J. 15:41-54. Link to the paper: https://rdcu.be/b64QP. *equal contribution
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2020 Goldin, S., Y. Hulata, N. Baran and D. Lindell. Quantification of T4-like and T7-like cyanophages using the polony method show they are significant members of the virioplankton in the North Pacific Subtropical Gyre. Frontiers in Microbiology. 11:1210.
Link to the paper: https://t.co/mkL9YpmrA3.
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2019 Zborowsky, S. and D. Lindell. Resistance in marine cyanobacteria differs against specialist and generalist cyanophages. Proc. Natl. Acad. Sci. USA. 116:16899-16908.
Link to the paper: https://www.pnas.org/content/early/2019/08/02/1906897116
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2018 Enav, H., S, Kirzner, D. Lindell, Y. Mandel-Gutfreund, O. Beja. Adaptation to sub-optimal hosts is a driver of viral diversification in the ocean. Nature Communications. 9:4698. Link to the paper: https://www.nature.com/articles/s41467-018-07164-3
2018 Berube, P.M., S. Biller, T. Hackl, S.L. Hogle, B.M. Satinsky, Jamie W. Becker1, Rogier Braakman, Sara B. Collins1, L.Kelly, J. Berta-Thompson, A. Coe, K. Bergauer, H.A. Bouman, T.J. Browning, D. De Corte, C. Hassler, Y. Hulata, J.E. Jacquot, E.W. Maas, T. Reinthaler, E. Sintes, T. Yokokawa, D. Lindell, R. Stepanauskas and . S.W. Chisholm. Single cell genomes of Prochlorococcus, Synechococcus, and sympatric microbes from diverse marine environments. Scientific Data 5:180154. Link to the paper: https://www.nature.com/articles/sdata2018154
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2018 Baran, N., S. Goldin, I. Maidanik, D. Lindell. Quantification of diverse virus populations in the environment using the polony method. Nature Microbiology 3:62-72. doi:10.1038/s41564-017-0045-y. Link to the paper: http://rdcu.be/xU0k.
2017 Fridman, S., O. Alalouf, B. Bailleul, F. Rappaport, A. Philosof, T. Ziv, O. Kleifeld, I. Sharon, C.L. Dupont, F.M. Cornejo-Castillo, P. Sánchez, S.G. Acinas, F. Rohwer, D. Lindell*, O. Béjà , O.*. A novel myovirus encoding both photosystem- I and II proteins enhances cyclic electron flow in infected Prochlorococcus cells. Nature Microbiology 2:1350-1357. doi:10.1038/s41564-017-0002-9. *corresponding authors. Link to the paper: http://rdcu.be/uOd3.
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2017 Fedida, A. and D. Lindell. Two Synechococcus genes, two different effects on cyanophage infection. Viruses. 9:136. doi:10.3390/v9060136. Link to the paper: https://www.mdpi.com/1999-4915/9/6/136
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2017 Schwartz, D.A. and D. Lindell. Genetic hurdles limit the arms race between Prochlorococcus and the T7-like podoviruses infecting it. ISME J. 11:1836-1851.
Link to the paper: https://www.nature.com/articles/ismej201747
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2016 Kirzner, S., E. Barak, D. Lindell. Variability in progeny production and virulence of cyanophages determined at the single-cell level. Environ. Microbiol. Reports. 8:605-613.
Link to the paper: https://enviromicro-journals.onlinelibrary.wiley.com/doi/10.1111/1758-2229.12409
2016 Stazic, D., I. Pekarsky, M. Kopf, D. Lindell, C. Steglich. A novel strategy for exploitation of host RNase E activity by a marine cyanophage. Genetics. 203:1149-1159. Link to the paper: https://academic.oup.com/genetics/article/203/3/1149/6065793
2016 Doron, S.*, A. Fedida*, M. Hernandez, G. Sabehi, I. Karunker, R. Feingersch, M. Futschik, D. Lindell#, R. Sorek#. Transcriptome dynamics of a broad host-range cyanophage and its hosts. ISME J. 10:1437-1455. *contributed equally, #corresponding authors. Link to the paper: https://www.nature.com/articles/ismej2015210
2015 Avrani, S. and D. Lindell. Convergent evolution toward an improved growth rate and a reduced resistance range in Prochlorococcus strains resistant to phage. Proc. Natl. Acad. Sci. 112:E2191-E2200.
Link to the paper: https://www.pnas.org/doi/full/10.1073/pnas.1420347112
2015 Steglich, C., D. Stazic, S. C. Lott, K. Boigt, E. Greengrass, D. Lindell, W. R. Hess. Dataset for metatranscriptome analysis of Prochlorococcus-rich marine picoplankton communities in the Gulf of Aqaba, Red Sea. Marine Genomics 19:5-7.
Link to the paper: https://www.sciencedirect.com/science/article/pii/S1874778714001299
2015 Biller, S. P. M. Berube, D. Lindell, S.W. Chisholm. Prochlorococcus: The structure and function of collective diversity. Nature Reviews Microbiology 13:13-27.
Link to the paper: https://www.nature.com/articles/nrmicro3378
2015 Dekel-Bird, N. P., G. Sabehi, B. Mosevitzky, D. Lindell. Host-dependent differences in abundance, composition and host-range of cyanophages from the Red Sea. Environmental Microbiology 17:1286-1299.
Link to the paper: https://enviromicro-journals.onlinelibrary.wiley.com/doi/10.1111/1462-2920.12569
2014 Lindell, D. The Genus Prochlorococcus, Phylum Cyanobacteria. In: E. Rosenberg, E. Stackebrandt, E. DeLong, S. Lory, F. L. Thompson (Ed.) The Prokaryotes – Other Major Lineages of Bacteria and the Archaea, 4th Edition. Springer. Vol 11, Chapter 65, pp 829-845.
Link to the paper: https://link.springer.com/referenceworkentry/10.1007/978-3-642-38954-2_125
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2013 Dekel-Bird, N.P., S. Avrani, G. Sabehi, M. Marston, S. Kirzner, D. Lindell. Diversity and evolutionary relationships of podoviruses infecting marine cyanobacteria. Environmental Microbiology 15:1476-1491. Link to the paper:
https://enviromicro-journals.onlinelibrary.wiley.com/doi/10.1111/1462-2920.12103
2012 Sabehi, G., L. Shaulov, D. Silver, I. Yanai, A. Harel, D. Lindell. A novel lineage of myoviruses infecting marine cyanobacteria is widespread in the oceans. Proc. Nat. Acad. Sci. 109:2037-2042.
Link to the paper: https://www.pnas.org/doi/full/10.1073/pnas.1115467109
2012 Avrani*, S., D.A. Schwartz*, D. Lindell. Virus-host swinging party in the oceans: Incorporating biological complexity into paradigms of antagonistic coexistence. *contributed equally to this work. Mobile Genetic Elements 2:88-95.
Link to the paper: https://www.tandfonline.com/doi/full/10.4161/mge.20031
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2012 Sabehi, G. and D. Lindell. The P-SSP7 cyanophage has a linear genome with direct terminal repeats. PLoS ONE, 7:e36710.
Link to the paper: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0036710
2011 Avrani, S., O. Wurtzel, I. Sharon, R. Sorek, D. Lindell. Genomic island variability facilitates Prochlorococcus-virus coexistence. Nature 474:604-608. Link to the paper: https://www.nature.com/articles/nature10172
See News & Views about this study: Nature 474:582-583, (2011).
2011 Stazic, D., D. Lindell, C. Steglich. Antisense RNA protects mRNA from RNase E degradation by RNA-RNA duplex formation during phage infection. Nucleic Acids Research 39:4890-4899.
Link to the paper: https://academic.oup.com/nar/article/39/11/4890/1142617
2010 Steglich, C., D. Lindell, M.E. Futschik, T. Rector, R. Steen and S.W. Chisholm. Short RNA half-lives in the slow-growing marine cyanobacterium Prochlorococcus. Genome Biology 19:11:R54.
Link to the paper: https://genomebiology.biomedcentral.com/articles/10.1186/gb-2010-11-5-r54
2009 Zinser, E.R., D. Lindell, Z.I. Johnson, M.E. Futschik, C. Steglich, M.L. Coleman, M.A. Wright, T. Rector, R. Steen, N. McNulty, L.R. Thompson, and S.W. Chisholm. Choreography of the transcriptome, photophysiology, and cell cycle of a minimal photoautotroph, Prochlorococcus. PLoS ONE 4:e5135.
Link to the paper: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0005135
2009 Rohwer, F. D. Prangishvili, D. Lindell. Roles of viruses in the environment. Environmental Microbiology 11:2771-2774. Link to the paper:
https://enviromicro-journals.onlinelibrary.wiley.com/doi/pdf/10.1111/j.1462-2920.2009.02101.x
Editorial for Special Issue on Environmental Viruses
2009 Allen, M.J., B. Tiwari, M.E. Futschik, D. Lindell. Methods in aquatic viral ecology: Construction of microarrays and their application to virus analysis. Manual of Aquatic Viral Ecology (MAVE) Chapter 5: 34-56. Link to the paper: https://www.aslo.org/wp-content/uploads/MAVE_034.pdf
Published by The American Society for Limnology and Oceanography, Inc.
2008 Steglich, C., M.E. Futschik, D. Lindell, B. Voss, S.W. Chisholm, W.R. Hess. The challenge of regulation in a minimal phototroph: Non-coding RNAs in Prochlorococcus. PLoS Genetics 4:e1000173.
Link to the paper: https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1000173
2008 Comeau*, A.M., G.F. Hatfull*, H.M. Krisch*, D. Lindell*, N.H. Mann*, D. Prangishvili*. Exploring the prokaryotic virosphere. Research in Microbiology 159:306-313. Link to the paper:
https://www.sciencedirect.com/science/article/pii/S092325080800082X *All authors contributed equally, alphabetical order.
2007 Lindell, D., J.D. Jaffe, M.L. Coleman, M.E. Futschik, I. Axmann, T. Rector, G. Kettler, M.B. Sullivan, R. Steen, W. Hess, G.M. Church, S.W. Chisholm. Genome-wide expression dynamics of a marine virus and host reveal features of co-evolution. Nature 449:83-86.
Link to the paper: https://www.nature.com/articles/nature06130
See Faculty of 1000 evaluation, Nature Reviews Microbiology, and ASM current topics write-ups of this work.
2007 Moore, L.R., A. Coe, E. Zinser, M. Saito, M.B. Sullivan, D. Lindell, K. Frois-Moniz, J. Waterbury, S.W. Chisholm. Culturing the marine cyanobacterium Prochlorococcus. Limnology and Oceanography Methods 5:353-362. Link to the paper:
2006 Penno, S., D. Lindell, A.F. Post. Biodiversity of Synechococcus and Prochlorococcus populations determined from DNA sequences of the N-regulatory gene ntcA. Environmental Microbiology 8:1200-1211. Link to the paper: https://enviromicro-journals.onlinelibrary.wiley.com/doi/full/10.1111/j.1462-2920.2006.01010.x
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2006 Tolonen, A., J. Aach, D. Lindell, Z.I. Johnson, T. Rector, R. Steen, G.M. Church, S.W. Chisholm. Global gene expression of Prochlorococcus in response to changes in nitrogen availability. Molecular Systems Biology 2:53. Link to the paper: https://www.embopress.org/doi/full/10.1038/msb4100087
2006 Sullivan*, M.B., D. Lindell*, J.A. Lee, L. Thompson, J. Bielawski, S.W. Chisholm. Prevalence and evolution of core photosystem II genes in marine cyanobacterial viruses and their hosts. PLoS Biology 4:e234.
*contributed equally to this work. See Faculty of 1000 evaluations, Nature Reviews Microbiology and Science Editors choice write-ups of this work.
Link to the paper: https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.0040234
2005 Lindell, D., J.D. Jaffe, Z.I. Johnson, G.M. Church, S.W. Chisholm. Photosynthesis genes in marine viruses yield proteins during host infection. Nature 438:86-89.
See Faculty of 1000 evaluations, The Scientist and Blackwell Plant Science News write-ups of this work.
Link to the paper: https://www.nature.com/articles/nature04111
2005 Lindell, D., S. Penno, M. Al-Qutob, E. David, T. Korpal, B. Lazar, and A. F. Post. Expression of the nitrogen stress response gene ntcA reveals nitrogen sufficient Synechococcus populations in the oligotrophic northern Red Sea. Limnology and Oceanography 50:1932-1944. 3
Link to the paper: https://aslopubs.onlinelibrary.wiley.com/doi/pdf/10.4319/lo.2005.50.6.1932
2004 Lindell*, D., M. B. Sullivan*, Z. I. Johnson, A. C. Tolonen, F. Rohwer and S. W. Chisholm. Transfer of photosynthesis genes to and from Prochlorococcus viruses. Proc. Nat. Acad. Sci. 101:11013-11018.
*contributed equally to this work. See Faculty of 1000 evaluation of this work.
Link to the paper: https://www.pnas.org/doi/full/10.1073/pnas.0401526101
2003 Rocap, G., F. W. Larimer, J. Lamerdin, S. Malfatti, P. Chain, N. A. Ahlgren, A. Arellano, M. Coleman, L Hauser, W. R. Hess, Z. I. Johnson, M. Land, D. Lindell, A. F. Post, W. Regala, M. Shah, S. L. Shaw, C. Steglich, M. B. Sullivan, C. S. Ting, A. Tolonen, E. A. Webb, E. R. Zinser, S. W. Chisholm. Genome divergence in two Prochlorococcus ecotypes reflects oceanic niche differentiation. Nature 424:1042-1047. (Author list alphabetical from Ahlgren to Zinser)
Link to the paper: https://www.nature.com/articles/nature01947
2002 Lindell, D., D. Erdner, D. Marie, O. Prasil, M. Koblizek, F. Le Gall, R. Rippka, F. Partensky, D. J. Scanlan, and A. F. Post. The nitrogen stress response of Prochlorococcus strain PCC 9511 (Oxyphotobacteria) involves contrasting regulation of ntcA and amt1. Journal of Phycology 38:1113-1124. Link to the paper: https://onlinelibrary.wiley.com/doi/full/10.1046/j.1529-8817.2002.01205.x
2001 Lindell, D., and A. F. Post. Ecological aspects of ntcA gene expression and its use as an indicator of the nitrogen status of marine Synechococcus. Applied and Environmental Microbiology 67:3340-3349.
Link to the paper: https://journals.asm.org/doi/full/10.1128/aem.67.8.3340-3349.2001
2000 Angel, D.L., S. Verghese, J.J. Lee, A.M. Saleh, D. Zuber, D. Lindell, and A. Symons. Impact of a net cage fish farm on the distribution of benthic foraminifera in the northern Gulf of Eilat (Aqaba, Red Sea). Journal of Foraminiferal Research 30:54-65.
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1999 Lindell, D., E. Padan and A.F. Post. Effect of ammonium on nitrate/nitrite uptake and ntcA expression in Synechococcus sp. strain WH 7803. In: Marine Cyanobacteria. Charpy L. & Larkum AWD (eds). Bulletin de l’Institut Oceanographie, Monaco, special issue No. 19:273-278.
Link to the paper: https://horizon.documentation.ird.fr/exl-doc/pleins_textes/divers15-02/010019783.pdf#page=285
1998 Lindell, D., E. Padan and A.F. Post. Regulation of ntcA expression and nitrite uptake in the marine Synechococcus sp. strain WH 7803. Journal of Bacteriology 180:1878-1886.
Link to the paper: https://journals.asm.org/doi/full/10.1128/jb.180.7.1878-1886.1998
1995 Lindell, D., and A.F. Post. Ultraphytoplankton succession is triggered by deep winter mixing in the Gulf of Aqaba (Eilat), Red Sea. Limnology and Oceanography 40(6):1130-1141.
Link to the paper: https://aslopubs.onlinelibrary.wiley.com/doi/pdf/10.4319/lo.1995.40.6.1130
1993 Knibb, W., A., A. Colorni, M. Ankaoua, D. Lindell, A. Diamant and H. Gordin. Detection and identification of a pathogenic marine mycobacterium from the European seabass Dicentrarchus labrax using PCR and direct sequencing of 16S rDNA sequences. Molecular Marine Biology and Biotechnology 2:225-232.